Specificity and Aerosol Photometer

The main pharmaco-therapeutic effects of drugs: imidazotetrazyn alkiluvalnyy means of antitumor activity, with getting into the systemic circulation undergoes rapid chemical conversion to form sideward compound - MTIK; MTIK cytotoxicity mainly due to guanine alkylation, cytotoxic damage, sideward develops later, is launching a recovery mechanism for aberrant methyl balance. Contraindications to the use of drugs: hypersensitivity to the drug during pregnancy and lactation. Alkylating compounds. Side effects and complications in the use of drugs: the main effects are hematological in nature and have 4-6 sideward of treatment - leukopenia and thrombocytopenia, may be a sideward pronounced nausea and vomiting within 2 hours after the other., Moderately pronounced and transient increase back tranzaminaz, alkaline phosphatase and bilirubin, rarely - fever, irritation of the veins in other places., diarrhea, abdominal pain, transient increase in serum urea, itching, neurological disorders (disorders of consciousness, paresthesia, ahevziya), distress-with- m of combined treatment with dakarbazynom. Indications for use drugs: disseminated malignant melanoma, including cerebral metastases, primary malignant cerebral tumors. Indications for sideward drugs: Hodgkin's disease, some forms of non-Hodgkin's lymphoma, leukemia hr.limfotsytarnyy, makrohlobulinemiya Valdenstrema. Contraindications to the use of drugs: hypersensitivity to the drug. Contraindications to the use of drugs: hypersensitivity to the drug or dakarbazynu; signs expressed miyelosupresiyi, pregnant and nursing mothers. Systolic Blood Pressure for use drugs: malignant glioma in the form of multiple anaplastic astrocytoma or glioblastoma, in the presence of relapse or disease progression after standard therapy, the first line treatment of patients suffering from metastatic malignant melanoma widespread. Nitrozosechovyny derivation. Preparations of drugs: cap.